免疫原
Synthesized peptide derived from human SOAT2
特异性
This antibody detects endogenous levels of SOAT2 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol . Plays a role in lipoprotein assembly and dietary cholesterol absorption . Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) and linolenoyl-CoA ((9Z,12Z,15Z)-octadecatrienoyl-CoA) as substrates . May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa . ; [Isoform 2]: Has lower enzymatic activity compared to isoform 1. ; [Isoform 3]: Has lower enzymatic activity compared to isoform 1.
基因名称(Gene Name)
SOAT2 ACACT2 ACAT2
蛋白名称
Sterol O-acyltransferase 2 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
组织表达
Expression seems confined in hepatocytes and enterocytes.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)