免疫原
Synthesized peptide derived from human UCHL5
特异性
This antibody detects endogenous levels of UCHL5 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.
基因名称(Gene Name)
UCHL5 UCH37 AD-019 CGI-70
蛋白名称
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
细胞定位
Cytoplasm . Nucleus . Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)