免疫原
Synthesized peptide derived from human CAPG
特异性
This antibody detects endogenous levels of CAPG at Human,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
基因名称(Gene Name)
CAPG AFCP MCP
蛋白名称
Macrophage-capping protein (Actin regulatory protein CAP-G)
组织表达
Nucleus . Cytoplasm . Melanosome . Cell projection, lamellipodium . Cell projection, ruffle . In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)