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TRP1 mouse mAb

BYmab-18080

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
59kD
免疫原
Synthesized peptide derived from human TRP1
特异性
This antibody detects endogenous levels of TRP1 at Human, Mouse
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
功能
Plays a role in melanin biosynthesis . Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+) . May regulate or influence the type of melanin synthesized . Also to a lower extent, caMABle of hydroxylating tyrosine and producing melanin (By similarity).
基因名称(Gene Name)
TYRP1 CAS2 TYRP TYRRP
蛋白名称
5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) (EC 1.14.18.-) (Catalase B) (Glycoprotein 75) (Melanoma antigen gp75) (Tyrosinase-related protein 1) (TRP) (TRP-1) (TRP1)
简称
其他名称
Fields
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
组织表达
Pigment cells.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)

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TRP1 mouse mAb

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