欢迎访问南京博研生物官网 服务热线:025-52298998 |
您当前的位置: 首页 > 产品中心 > 一抗 > 单克隆抗体

CCDC88C mouse mAb

BYmab-18058

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

产品简介 实验方案 引用文献 相关产品

产品简介>

宿主
反应性
应用
WB
分子量(DA)
223kD
免疫原
Synthesized peptide derived from human CCDC88C
特异性
This antibody detects endogenous levels of CCDC88C at Human, Mouse
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
功能
Required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling . Binds to ligand-activated Wnt receptor FZD7, displacing DVL1 from the FZD7 receptor and leading to inhibition of canonical Wnt signaling . Acts as a non-receptor guanine nucleotide exchange factor by also binding to guanine nucleotide-binding protein G(i) alpha (Gi-alpha) subunits, leading to their activation . Binding to Gi-alpha subunits displaces the beta and gamma subunits from the heterotrimeric G-protein complex, triggering non-canonical Wnt responses such as activation of RAC1 and PI3K-AKT signaling . Promotes apical constriction of cells via ARHGEF18 .
基因名称(Gene Name)
CCDC88C DAPLE KIAA1509
蛋白名称
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
简称
其他名称
Fields
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm . Cell junction . Enriched at apical cell junctions. .
组织表达
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)

实验方案>

实验步骤

引用文献(0)>

成功添加到购物车

查看购物车 继续购物

CCDC88C mouse mAb

筛选器: All

亮暗模式切换
X

在线
客服

在线客服
09:00 - 18:00

服务热线

服务
热线

客服服务热线

025-52298998
客服服务热线

扫码

扫码
咨询

微信二维码 微信扫一扫立即咨询
返回顶部 顶部