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NR0B2 mouse mAb

BYmab-17755

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
Calculated MW: 28 kDa; Observed MW: 28 kDa
免疫原
Recombinant fusion protein containing a sequence of human NR0B2 (NP_068804.1).
特异性
来源
组成(Formulation)
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
浓度
背景(Background)
The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.
功能
基因名称(Gene Name)
NR0B2
蛋白名称
简称
其他名称
NR0B2; SHP; SHP1; nuclear receptor subfamily 0 group B member 2
Fields
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
组织表达
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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NR0B2 mouse mAb

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