免疫原
SynSynthesized peptide derived from human RHBDF2thesized peptide derived from human RHBDF2
特异性
This antibody detects endogenous levels of RHBDF2 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.1157% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
基因名称(Gene Name)
RHBDF2 IRHOM2 RHBDL5 RHBDL6
蛋白名称
Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane .
组织表达
Found in the epidermis and esophageal epithelium.
储存(Storage)
‘-15°C to -25°C/1 year(Do not lower than -25°C)