免疫原
The antiserum was produced against synthesized peptide derived from human BRD3. AA range:611-660
特异性
BRD3 Monoclonal Antibody detects endogenous levels of BRD3 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008],
功能
disease:A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.,similarity:Contains 2 bromo domains.,tissue specificity:Ubiquitous.,
蛋白名称
Bromodomain-containing protein 3
其他名称
BRD3; KIAA0043; RING3L; Bromodomain-containing protein 3; RING3-like protein
细胞定位
Nucleus . Detected on chromatin. .