免疫原
The antiserum was produced against synthesized peptide derived from human GABA-RB. AA range:401-450
特异性
GABAA Rβ1 Monoclonal Antibody detects endogenous levels of GABAA Rβ1 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008],
功能
function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,online information:Forbidden fruit - Issue 56 of March 2005,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.,
蛋白名称
Gamma-aminobutyric acid receptor subunit beta-1
其他名称
GABRB1; Gamma-aminobutyric acid receptor subunit beta-1; GABA(A) receptor subunit beta-1
Fields
>>Neuroactive ligand-receptor interaction;>>Retrograde endocannabinoid signaling;>>Serotonergic synapse;>>GABAergic synapse;>>Morphine addiction;>>Nicotine addiction
细胞定位
Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .
联系我们
关注我们
您当前的位置： 
成功添加到购物车
