免疫原
The antiserum was produced against synthesized peptide derived from human RAB3IP. AA range:257-306
特异性
RAB3IP Monoclonal Antibody detects endogenous levels of RAB3IP protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
similarity:Belongs to the SEC2 family.,subcellular location:Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus.,subunit:Interacts with the N-terminal region of SSX2. Interacts with RAB3A and RAB3D.,tissue specificity:Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.,
功能
similarity:Belongs to the SEC2 family.,subcellular location:Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus.,subunit:Interacts with the N-terminal region of SSX2. Interacts with RAB3A and RAB3D.,tissue specificity:Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.,
蛋白名称
Rab-3A-interacting protein
其他名称
RAB3IP; RABIN8; Rab-3A-interacting protein; Rab3A-interacting protein; Rabin-3; SSX2-interacting protein
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton . Cell projection, lamellipodium. Vesicle . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. .
组织表达
Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or liver.