免疫原
The antiserum was produced against synthesized peptide derived from human RAB34. AA range:206-255
特异性
Rab 34 Monoclonal Antibody detects endogenous levels of Rab 34 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame. [provided by RefSeq, Jan 2012],
功能
function:Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region.,similarity:Belongs to the small GTPase superfamily. Rab family.,subcellular location:Associates with the Golgi complex.,subunit:Interacts with RILP.,
蛋白名称
Ras-related protein Rab-34
其他名称
RAB34; RAB39; RAH; Ras-related protein Rab-34; Ras-related protein Rab-39; Ras-related protein Rah
细胞定位
Cytoplasm . Golgi apparatus . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Cell projection, cilium . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). .
组织表达
Brain,Embryo,Heart,Mammary gland,Pancreas,Skeletal muscle,