免疫原
Synthesized peptide derived from ARHGAP12 . at AA range: 310-390
特异性
ARHGAP12 Monoclonal Antibody detects endogenous levels of ARHGAP12 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
功能
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 WW domains.,
蛋白名称
Rho GTPase-activating protein 12
其他名称
ARHGAP12; Rho GTPase-activating protein 12; Rho-type GTPase-activating protein 12
组织表达
PCR rescued clones,Placenta,T-cell,Testis,Uterus,