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CCL17 Monoclonal Antibody

BYmab-16094

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
10kD
免疫原
Synthesized peptide derived from human CCL17 AA range: 21-70
特异性
This antibody detects endogenous levels of human CCL17
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
背景(Background)
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014],
功能
caution:Was originally (PubMed:9521068) thought to be a ligand for CCR8.,function:Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.,induction:By phytohemagglutinin (PHA) in the peripheral blood mononuclear cells and by cytokines in monocytes.,online information:CCL17 entry,similarity:Belongs to the intercrine beta (chemokine CC) family.,tissue specificity:Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.,
基因名称(Gene Name)
CCL17 SCYA17 TARC
蛋白名称
CCL17
简称
CCL17
其他名称
C-C motif chemokine 17 (CC chemokine TARC;Small-inducible cytokine A17;Thymus and activation-regulated chemokine)
Fields
>>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>C-type lectin receptor signaling pathway;>>IL-17 signaling pathway
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted.
组织表达
Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.
储存(Storage)
-20°C/1 year

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CCL17 Monoclonal Antibody

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