免疫原
The antiserum was produced against synthesized peptide derived from human VIP. AA range:71-120
特异性
VIP Monoclonal Antibody detects endogenous levels of VIP protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014],
功能
function:PHM and PHV also cause vasodilation.,function:VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.,online information:Vasoactive intestinal peptide entry,similarity:Belongs to the glucagon family.,
Fields
>>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction
组织表达
Pancreatic carcinoma,Pheochromocytoma,Prostate,