免疫原
The antiserum was produced against synthesized peptide derived from human STK17B. AA range:251-300
特异性
DRAK2 Monoclonal Antibody detects endogenous levels of DRAK2 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Acts as a positive regulator of apoptosis.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.,tissue specificity:Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.,
蛋白名称
Serine/threonine-protein kinase 17B
其他名称
STK17B; DRAK2; Serine/threonine-protein kinase 17B; DAP kinase-related apoptosis-inducing protein kinase 2
细胞定位
Nucleus . Cell membrane . Endoplasmic reticulum-Golgi intermediate compartment . Colocalizes with STK17B at the plasma membrane. .
组织表达
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
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