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C7 Monoclonal Antibody

BYmab-14089

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
93kD
免疫原
The antiserum was produced against synthesized peptide derived from the N-terminal region of human C7. AA range:100-150
特异性
C7 Monoclonal Antibody detects endogenous levels of C7 protein.
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008],
功能
disease:Defects in C7 are a cause of component C7 deficiency (C7D) [MIM:217070]. Patients with C7D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis.,function:C7 is a constituent of the membrane attack complex. C7 binds to C5b forming the C5b-7 complex, where it serves as a membrane anchor.,online information:C7 mutation db,PTM:C7 has 28 disulfide bridges.,similarity:Belongs to the complement C6/C7/C8/C9 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 MACPF domain.,similarity:Contains 2 Sushi (CCP/SCR) domains.,similarity:Contains 2 TSP type-1 domains.,subunit:Monomer or dimer; as a C5b-7 complex it can also form multimeric rosettes.,
基因名称(Gene Name)
C7
蛋白名称
Complement component C7
简称
C7
其他名称
C7; Complement component C7
Fields
>>Complement and coagulation cascades;>>Prion disease;>>Coronavirus disease - COVID-19;>>Systemic lupus erythematosus
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted.
组织表达
Liver,Placenta,Plasma,PNS,
储存(Storage)
-20°C/1 year

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C7 Monoclonal Antibody

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