免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human LILRA4. AA range:391-440
特异性
CD85g Monoclonal Antibody detects endogenous levels of CD85g protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015],
功能
function:May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected on eosinophils, neutrophils and monocytes.,
蛋白名称
Leukocyte immunoglobulin-like receptor subfamily A member 4
其他名称
LILRA4; ILT7; Leukocyte immunoglobulin-like receptor subfamily A member 4; CD85 antigen-like family member G; Immunoglobulin-like transcript 7; ILT-7; CD85g
Fields
>>Osteoclast differentiation;>>B cell receptor signaling pathway
细胞定位
Cell membrane ; Single-pass type I membrane protein .
组织表达
Detected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells.
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