免疫原
Synthesized peptide derived from the Internal region of human Hepassocin.
特异性
Hepassocin Monoclonal Antibody detects endogenous levels of Hepassocin protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
fibrinogen like 1(FGL1) Homo sapiens Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008],
功能
function:Has hepatocyte mitogenic activity.,similarity:Contains 1 fibrinogen C-terminal domain.,subunit:Homodimer.,tissue specificity:Liver specific.,
蛋白名称
Fibrinogen-like protein 1
其他名称
FGL1; HFREP1; Fibrinogen-like protein 1; HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1
细胞定位
Secreted . Secreted in the blood plasma. .
组织表达
Under normal conditions, liver-specific.
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