免疫原
The antiserum was produced against synthesized peptide derived from human FKBPL. AA range:251-300
特异性
FKBPL Monoclonal Antibody detects endogenous levels of FKBPL protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008],
功能
function:May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 3 TPR repeats.,subunit:Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.,tissue specificity:Ubiquitously expressed with higher levels in testis.,
蛋白名称
FK506-binding protein-like
其他名称
FKBPL; DIR1; NG7; FK506-binding protein-like; WAF-1/CIP1 stabilizing protein 39; WISp39
细胞定位
endoplasmic reticulum membrane,cytosol,
组织表达
Ubiquitously expressed with higher levels in testis.
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