分子量(DA)
Calculated MW: 46 kDa; Observed MW: 46 kDa
免疫原
Fusion protein of human TNFRSF11B Purification Affinity Purified Conjugation
Unconjugated Modification Unmodified Form Liquid
背景(Background)
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
基因名称(Gene Name)
TNFRSF11B
简称
TNFRSF11B; OCIF; OPG; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.