免疫原
The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350
特异性
GPR50 Monoclonal Antibody detects endogenous levels of GPR50 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010],
功能
function:Does not bind melatonin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Hypothalamus and pituitary.,
蛋白名称
Melatonin-related receptor
其他名称
GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9
Fields
>>Neuroactive ligand-receptor interaction
细胞定位
Cell membrane; Multi-pass membrane protein.
组织表达
Hypothalamus and pituitary.
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