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TBCD mouse mAb

BYmab-11290

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
免疫原
Synthesized peptide derived from human TBCD AA range: 419-469
特异性
This antibody detects endogenous levels of TBCD at Human/Mouse
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
背景(Background)
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008],
功能
function:Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB).,induction:Down-regulated by shear stress.,similarity:Belongs to the TBCD family.,similarity:Contains 3 HEAT repeats.,subunit:Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.,tissue specificity:Ubiquitously expressed.,
基因名称(Gene Name)
TBCD KIAA0988 SSD1 TFCD PP1096
蛋白名称
TBCD
简称
TBCD
其他名称
Fields
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cell junction, tight junction . Lateral cell membrane . Cytoplasm . Cell junction, adherens junction . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localized in cell-cell contacts. .
组织表达
Ubiquitously expressed.
储存(Storage)
-20°C/1 year

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TBCD mouse mAb

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