免疫原
Synthesized peptide derived from human FBX46 AA range: 67-117
特异性
This antibody detects endogenous levels of FBX46 at Human/Mouse/Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景（Background）
Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],
功能
caution:The region from 1 to 163 was deduced from the genomic sequence and ESTs by similarity to the mouse sequence.,function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,subunit:Interacts with SKP1A and CUL1.,
基因名称（Gene Name）
FBXO46 FBX46 FBXO34L
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