欢迎访问南京博研生物官网 服务热线:025-52298998 |
您当前的位置: 首页 > 产品中心 > 一抗 > 单克隆抗体

Gremlin-2 Monoclonal Antibody

BYmab-10648

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

产品简介 实验方案 引用文献 相关产品

产品简介>

宿主
反应性
应用
WB
分子量(DA)
19kD
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human GREM2. AA range:71-120
特异性
The antibody detects endogenous Gremlin-2
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],
功能
function:Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.,similarity:Belongs to the DAN family.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,subunit:Interacts with BMP2 and BMP4.,
基因名称(Gene Name)
GREM2 CKTSF1B2 DAND3 PRDC
蛋白名称
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)
简称
Gremlin-2
其他名称
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2;DAN domain family member 3;Protein related to DAN and cerberus)
Fields
>>TGF-beta signaling pathway
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted .
组织表达
Brain,Colon,
储存(Storage)
-20°C/1 year

实验方案>

实验步骤

引用文献(0)>

相关产品>

成功添加到购物车

查看购物车 继续购物

Gremlin-2 Monoclonal Antibody

筛选器: All

亮暗模式切换
X

在线
客服

在线客服
09:00 - 18:00

服务热线

服务
热线

客服服务热线

025-52298998
客服服务热线

扫码

扫码
咨询

微信二维码 微信扫一扫立即咨询
返回顶部 顶部