免疫原
Synthesized phosho peptide around human Rac1 (Ser71)
特异性
This antibody detects endogenous levels of Human Rac1/cdc42 (phospho-Ser71)
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
其他名称
Cell division control protein 42 homolog (G25K GTP-binding protein)
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Midbody . Cell projection, dendrite . Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase (PubMed:15642749). Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells (PubMed:15642749). Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1 (PubMed:15642749). Colocalizes with NEK6 in the centrosome (PubMed:20873783). In its active GTP-bound form localizes to the leading edge membrane of migrating dendritic cells (By similarity). .
组织表达
Brain,Cajal-Retzius cell,Cervix,Embryo,Fetal brain,Fetal brain cortex,Placenta,Uter