免疫原
Synthesized peptide derived from human PDK4 AA range: 34-84
特异性
This antibody detects endogenous levels of PDK4 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
背景（Background）
Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis.
基因名称（Gene Name）
PDK4 PDHK4
其他名称
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4)
Fields
>>Diabetic cardiomyopathy
细胞定位
Mitochondrion matrix.
组织表达
Ubiquitous; highest levels of expression in heart and skeletal muscle.
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