免疫原
Synthesized peptide derived from human PKHH2 AA range: 565-615
特异性
This antibody detects endogenous levels of human PKHH2
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
基因名称(Gene Name)
PLEKHH2 KIAA2028
蛋白名称
Pleckstrin homology domain-containing family H member 2
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, lamellipodium . Localizes to foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K.
组织表达
Kidney. Reduced expression in patients with focal segmental glomerulosclerosis.