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WDR36 mouse mAb

BYmab-08104

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
105kD
免疫原
Synthesized peptide derived from human WDR36 AA range: 607-657
特异性
This antibody detects endogenous levels of WDR36 at Human
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.219% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse serum by affinity-chromatography using specific immunogen.
浓度
1 mg/ml
背景(Background)
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG). [provided by RefSeq, Jul 2008],
功能
disease:Defects in WDR36 are the cause of primary open angle glaucoma type 1G (GLC1G) [MIM:609887]. Primary open angle glaucoma (POAG) is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.,function:Involved in T cell activation and highly co-regulated with IL2.,similarity:Contains 9 WD repeats.,tissue specificity:Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve.,
基因名称(Gene Name)
WDR36
蛋白名称
WDR36
简称
WDR36
其他名称
WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)
Fields
>>Ribosome biogenesis in eukaryotes
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus, nucleolus .
组织表达
Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve.
储存(Storage)
-20°C/1 year

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WDR36 mouse mAb

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