免疫原
Synthesized peptide derived from human protein . at AA range: 181-230
特异性
TMM74 Monoclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
TMEM74 (Transmembrane Protein 74) is a Protein Coding gene. An important paralog of this gene is TMEM74B. Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction.
蛋白名称
Transmembrane protein 74
细胞定位
Lysosome membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Multi-pass membrane protein .
组织表达
Expressed in heart, lung, and placenta.