免疫原
Synthesized peptide derived from human protein . at AA range: 360-440
特异性
PTHD2 Monoclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
developmental stage:Expressed in fetal brain.,similarity:Belongs to the patched family.,similarity:Contains 1 SSD (sterol-sensing) domain.,tissue specificity:Expressed in brain and testis.,
功能
developmental stage:Expressed in fetal brain.,similarity:Belongs to the patched family.,similarity:Contains 1 SSD (sterol-sensing) domain.,tissue specificity:Expressed in brain and testis.,
基因名称(Gene Name)
PTCHD2 DISP3 KIAA1337
蛋白名称
Patched domain-containing protein 2 (Protein dispatched homolog 3)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Nucleus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Predominantly localized to cholesterol-enriched domains within the membrane (PubMed:19179482). Localizes to cytoplasmic punctate vesicular structures (By similarity). .
组织表达
Expressed in brain and testis (PubMed:15645143).