免疫原
Synthesized peptide derived from part region of human protein
特异性
CCD80 Monoclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Promotes cell adhesion and matrix assembly.,induction:Down-regulated in cancer and after osteoblastic differentiation. Up-regulated by dihydrotestosterone (DHT).,PTM:Phosphorylated.,similarity:Belongs to the CCDC80 family.,subunit:Binds to various extracellular matrix proteins.,tissue specificity:Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.,
功能
function:Promotes cell adhesion and matrix assembly.,induction:Down-regulated in cancer and after osteoblastic differentiation. Up-regulated by dihydrotestosterone (DHT).,PTM:Phosphorylated.,similarity:Belongs to the CCDC80 family.,subunit:Binds to various extracellular matrix proteins.,tissue specificity:Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.,
基因名称(Gene Name)
CCDC80 DRO1 URB HBE245
蛋白名称
Coiled-coil domain-containing protein 80 (Down-regulated by oncogenes protein 1) (Up-regulated in BRS-3 deficient mouse homolog)
细胞定位
Secreted, extracellular space, extracellular matrix .
组织表达
Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts.