免疫原
Synthesized peptide derived from human protein . at AA range: 130-210
特异性
FN3K Monoclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012],
功能
function:May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme.,similarity:Belongs to the fructosamine kinase family.,subunit:Monomer.,tissue specificity:Expressed in erythrocytes.,
蛋白名称
Fructosamine-3-kinase (EC 2.7.1.-)
组织表达
Widely expressed (PubMed:11522682). Expressed in erythrocytes (PubMed:11016445).