免疫原
Synthesized peptide derived from human protein . at AA range: 170-250
特异性
DIRC2 Monoclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined. [provided by RefSeq, Jul 2008],
功能
disease:A chromosomal aberration involving DIRC2 is found in familial renal cell carcinoma 1 (RCC1) [MIM:144700]. Translocation t(2;3)(q35;q21).,similarity:Belongs to the major facilitator superfamily.,tissue specificity:Ubiquitous. Expressed in proximal tubular cells of the kidney.,
蛋白名称
Disrupted in renal carcinoma protein 2 (Disrupted in renal cancer protein 2)
细胞定位
Lysosome membrane ; Multi-pass membrane protein .
组织表达
Ubiquitous. Expressed in proximal tubular cells of the kidney.
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