免疫原
Synthesized peptide derived from human protein . at AA range: 310-390
特异性
LZTR1 Monoclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Gogli complex. Deletion of this gene may be associated with DiGeorge syndrome. [provided by RefSeq, Jul 2008],
功能
developmental stage:Expressed in fetal brain, heart, kidney, liver and lung.,disease:May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).,function:Probable transcriptional regulator that may play a crucial role in embryogenesis.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 Kelch repeats.,
基因名称（Gene Name）
LZTR1 TCFL2
蛋白名称
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)
细胞定位
Endomembrane system . Recycling endosome . Golgi apparatus .
组织表达
Brain,Duodenal adenocarcinoma,Fetal brain,
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