免疫原
Synthesized peptide derived from human protein . at AA range: 20-100
特异性
PGRC1 Monoclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010],
功能
domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.,function:Receptor for progesterone.,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Widely expressed, with highest expression in liver and kidney.,
基因名称(Gene Name)
PGRMC1 HPR6.6 PGRMC
蛋白名称
Membrane-associated progesterone receptor component 1 (mPR)
细胞定位
Microsome membrane ; Single-pass membrane protein . Smooth endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion outer membrane ; Single-pass membrane protein ; Extracellular side .
组织表达
Widely expressed, with highest expression in liver and kidney. Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472).