免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
LPPL Monoclonal Antibody detects endogenous levels of protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
蛋白名称
Eosinophil lysophospholipase (EC 3.1.1.5) (Charcot-Leyden crystal protein) (CLC) (Galectin-10) (Gal-10) (Lysolecithin acylhydrolase)
细胞定位
Cytoplasm, cytosol . Cytoplasmic granule . Localized in granules from where it may be secreted or transported to other locations in the cell.
组织表达
Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with Celiac disease, expression is directly related to the histological grade of mucosal damage and to the number of eosinophils found in the duodenal lesion (at protein level). Found in sputum of patients with eosinophilic inflammatory diseases such as asthma (at protein level).