免疫原
The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388
特异性
Arrestin-C Monoclonal Antibody detects endogenous levels of Arrestin-C protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016],
功能
function:May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.,similarity:Belongs to the arrestin family.,tissue specificity:Inner and outer segments, and the inner plexiform regions of the retina.,
其他名称
ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin
细胞定位
Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment .
组织表达
Inner and outer segments, and the inner plexiform regions of the retina.
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