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CA VIII Monoclonal Antibody

BYmab-02516

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
免疫原
Synthesized peptide derived from the Internal region of human CA VIII.
特异性
CA VIII Monoclonal Antibody detects endogenous levels of CA VIII protein.
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid
功能
function:Does not have a carbonic anhydrase catalytic activity.,similarity:Belongs to the alpha-carbonic anhydrase family.,
基因名称(Gene Name)
CA8
蛋白名称
Carbonic anhydrase-related protein
简称
CA VIII
其他名称
CA8; CALS; Carbonic anhydrase-related protein; CARP; Carbonic anhydrase VIII; CA-VIII
Fields
>>Nitrogen metabolism;>>Metabolic pathways
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
cytoplasm,
组织表达
储存(Storage)
-20°C/1 year

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CA VIII Monoclonal Antibody

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