免疫原
Synthesized peptide derived from human Smad1/5/9. at AA range: 291-340
特异性
Smad1/5/9 Monoclonal Antibody detects endogenous levels of Smad1/5/9
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
基因名称(Gene Name)
SMAD1/SMAD5/SMAD9
其他名称
Mothers against decapentaplegic homolog 1/5/9 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1/5/9) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
细胞定位
Cytoplasm . Nucleus . Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271). Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271). Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity). .
组织表达
Ubiquitous. Highest expression seen in the heart and skeletal muscle.