免疫原
Synthesized peptide derived from DNA Pol μ . at AA range: 210-290
特异性
DNA Pol μ Monoclonal Antibody detects endogenous levels of DNA Pol μ protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
功能
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
蛋白名称
DNA-directed DNA/RNA polymerase mu
其他名称
POLM; polmu; DNA-directed DNA/RNA polymerase mu; Pol Mu; Terminal transferase
Fields
>>Non-homologous end-joining
组织表达
Expressed in a number of tissues. Abundant in thymus.
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