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C/EBP ε Monoclonal Antibody

BYmab-01583

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3个工作日

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宿主
反应性
应用
WB
分子量(DA)
34kD
免疫原
The antiserum was produced against synthesized peptide derived from human C/EBP-epsilon. AA range:40-89
特异性
C/EBP ε Monoclonal Antibody detects endogenous levels of C/EBP ε protein.
来源
Monoclonal, Mouse,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],
功能
function:C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.,online information:CEBPE mutation db,PTM:Phosphorylated.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP delta.,tissue specificity:Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.,
基因名称(Gene Name)
CEBPE
蛋白名称
CCAAT/enhancer-binding protein epsilon
简称
C/EBP ε
其他名称
CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilon
Fields
>>Transcriptional misregulation in cancer;>>Acute myeloid leukemia
人基因ID
人蛋白质序列数据库
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus .
组织表达
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.
储存(Storage)
-20°C/1 year

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C/EBP ε Monoclonal Antibody

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