免疫原
The antiserum was produced against synthesized peptide derived from human ATF7. AA range:41-90
特异性
ATF-7 Monoclonal Antibody detects endogenous levels of ATF-7 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
function:Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Binds DNA as a dimer.,
功能
function:Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Binds DNA as a dimer.,
蛋白名称
Cyclic AMP-dependent transcription factor ATF-7
其他名称
ATF7; ATFA; Cyclic AMP-dependent transcription factor ATF-7; cAMP-dependent transcription factor ATF-7; Activating transcription factor 7; Transcription factor ATF-A
细胞定位
Nucleus . Nucleus, nucleoplasm . Chromosome, telomere . Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.; [Isoform 5]: Cytoplasm .
组织表达
Expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta. ; [Isoform 4]: Strongly expressed in skeletal muscle. Also expressed at lower levels in heart and lung.
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