免疫原
Synthesized peptide derived from the Internal region of human MxB.
特异性
MxB Monoclonal Antibody detects endogenous levels of MxB protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],
功能
induction:By interferons.,similarity:Belongs to the dynamin family.,similarity:Contains 1 GED domain.,
蛋白名称
Interferon-induced GTP-binding protein Mx2
其他名称
MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
Fields
>>Viral life cycle - HIV-1;>>Hepatitis C;>>Measles;>>Influenza A;>>Human papillomavirus infection;>>Coronavirus disease - COVID-19
细胞定位
Cytoplasm . Nucleus . Nucleus, nuclear pore complex . Localization to nuclear pores requires GTP-binding.
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