免疫原
Synthesized peptide derived from human QSOX1
特异性
This antibody detects endogenous levels of QSOX1 at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide . Plays a role in disulfide bond formation in a variety of extracellular proteins . In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration .
基因名称(Gene Name)
QSOX1 QSCN6 UNQ2520/PRO6013
蛋白名称
Sulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6)
细胞定位
[Isoform 1]: Golgi apparatus membrane ; Single-pass membrane protein . Secreted . A small proportion is secreted, probably via a proteolytic cleavage that removes the membrane anchor. .; [Isoform 2]: Secreted . Found in the extracellular medium of quiescent cells but is not found in proliferating cells. .
组织表达
Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)