免疫原
Synthesized peptide derived from human EIF4E2
特异性
This antibody detects endogenous levels of EIF4E2 at Human, Mouse
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation . Acts as a repressor of translation initiation . In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity). In P-bodies, component of a complex that promotes miRNA-mediated translational repression .
基因名称(Gene Name)
EIF4E2 EIF4EL3
蛋白名称
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3)
细胞定位
Cytoplasm . Cytoplasm, P-body .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)