免疫原
Synthesized peptide derived from human TIMM13
特异性
This antibody detects endogenous levels of TIMM13 at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
基因名称(Gene Name)
TIMM13 TIM13B TIMM13A TIMM13B
蛋白名称
Mitochondrial import inner membrane translocase subunit Tim13
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .
组织表达
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)