免疫原
Synthesized peptide derived from human FLAP
特异性
This antibody detects endogenous levels of FLAP at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
基因名称(Gene Name)
ALOX5AP FLAP
蛋白名称
Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)
细胞定位
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)