免疫原
Synthesized peptide derived from human FNDC5
特异性
This antibody detects endogenous levels of FNDC5 at Human, Mouse,Rat
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
[Irisin]: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
基因名称(Gene Name)
FNDC5 FRCP2
蛋白名称
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
细胞定位
Cell membrane ; Single-pass type I membrane protein . Peroxisome membrane ; Single-pass type I membrane protein . Imported in peroxisomes through the PEX5 receptor pathway. .; [Irisin]: Secreted. Detected in the blood of individuals subjected to endurance exercise. .
组织表达
Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)