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PSA (ABT114) Mouse mAb

说明书

BYab-17762

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
IHC;WB;IF
分子量(DA)
免疫原
Synthesized peptide derived from human PSA AA range: 100-200
特异性
The antibody can specifically recognize human PSA protein.. The antibody was also Predict react with Mouse;Rat
来源
Mouse, Monoclonal/IgG2b, Kappa
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1:200-400, WB 1:200-1000, IF 1:200-400
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度
背景(Background)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Preferential cleavage: -Tyr-|-Xaa-.,function:Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.,online information:Prostate-specific antigen entry,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,
基因名称(Gene Name)
KLK3 APS
蛋白名称
PSA
简称
其他名称
Prostate-specific antigen (PSA;EC 3.4.21.77;Gamma-seminoprotein;Seminin;Kallikrein-3;P-30 antigen;Semenogelase)
Fields
>>Pathways in cancer;>>Prostate cancer
人基因ID
354
人蛋白质序列数据库
P07288
小鼠基因ID
小鼠蛋白质序列数据库
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Secreted.
组织表达
Cytoplasmic
储存(Storage)
’-15°C to -25°C/1 year(Do not lower than -25°C)

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PSA (ABT114) Mouse mAb

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