分子量(DA)
Molecular Weight
Calculated MW: 56 kDa
免疫原
A synthesized peptide derived from human AKT1
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
背景(Background)
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
人基因ID
SwissProt ID
P31749
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.